Maddie and Alex get the facts about smoking!They learn the truth by interviewing Maddie's grandpa, Norman. His mistakes intrigue their class's journey to stay healthy and live smoke-free.

Linus becomes friends with Janice, a young girl who is diagnosed with leukemia. Despite all of the rumors and jokes, Linus learns that friendship is a very important part of Janice's recovery. He learns how to stand up for himself as well as others.

Mrs. K teaches Ann's third grade class. In class they are explorers, scientists, poets, and astronauts. They are always learning something new. One day, Mrs. K doesn't come to school. The students learn that she is in the hospital with cancer. For the rest of the year the third grade has a substitute. On the last day of school, Mrs. K comes back to surprise her students.

A young boy copes with his mother's cancer. Going through a range of emotions, he finally comes to more of an understanding about her illness.